The highest-seeded British duo had been overwhelmed 6-3 6-1 by the second seeds within the ultimate on Court docket Three.
Hewett and Reid had not misplaced a slam ultimate collectively since Wimbledon in 2019.
Alfie Hewett and Gordon Reid’s bid for an eleventh consecutive wheelchair doubles grand slam title was ended by Gustavo Fernandez and Shingo Kunieda at Wimbledon.
Their reign was delivered to a disappointing finish when Hewett double-faulted on match level.
Hewett faces high seed Kunieda of Japan within the singles ultimate on Sunday, having overwhelmed Argentinian Fernandez within the semi-final late on Friday evening.
Hewett stated: “We are able to’t take something away from these guys, they’ve been determined to beat us for a while now.
“Yesterday was an enormous day for myself, an unbelievable day that I’ll at all times bear in mind, so right this moment was difficult to go once more. However we’ll be again subsequent yr.”